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McDonald's Employee Reviews Review this company. Scientists, please ensure you read the background materials before registering. Cancer Genome Atlas Network Comprehensive molecular portraits of human breast tumours. Keywords: BRCA, somatic, germline, olaparib, ovarian. Dougherty1 Zhongwu Lai1 Darren R. Apply for About Research at The Christie.

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Ledermann8 and J. Phone: Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer. Attention to detail is required not only when comparing two sequencing assays, but also in the categorization of mutations, where occasional discrepancies may occur.

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Scientists, please ensure you read the background materials before registering. Furthermore, the ability of the assay to perform mutational analysis of hundreds of cancer genes at once provides insight into additional oncogenic drivers, mutational co-occurrence patterns, tumor heterogeneity, and the potential to identify homologous recombination and DNA repair genes beyond BRCA1 Online rummage sale Watford BRCA2 that may be involved in response to olaparib and other PARP inhibitors.

HRs and corresponding CIs were calculated from a Cox proportional hazards model using the same methods as reported for the primary analysis [ 10 ].

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